More Than Skin Deep: Why Skin Care Matters with PKD
When we think about Polycystic kidney disease (PKD) we usually think about the kidneys. But kidney disease can affect many parts of the body, including your skin.
As the body's largest organ, your skin works hard to protect you every day. Changes in kidney function, medications, treatments and even the weather can all affect your skin, so taking care of it can help improve your comfort and wellbeing.

When Your Skin Starts Complaining
Dry, itchy skin (known medically as pruritus) is a common problem for people with kidney disease. Skin may feel rough, flaky or uncomfortable, particularly on the arms, legs and back. Although it can start in the earlier stages of kidney disease, it often becomes more noticeable as kidney function declines and may even affect sleep. Many people find it gets worse during hot weather or periods of stress.
A few simple steps can help:
- Moisturise daily with a fragrance-free cream or lotion.
- Avoid very hot baths and showers.
- Use gentle, non-perfumed soaps and cleansers.
- Wear loose clothing made of natural fibres such as cotton.
- Stay well hydrated within the fluid limits recommended by your kidney team. Too little fluid may contribute to dry skin, while people with kidney disease often need to balance this carefully.
- Speak to your kidney team if itching becomes severe or persistent.
Some people may also notice changes in skin colour or find they bruise more easily as kidney disease progresses.
Skin and the Sun
Sun protection is important for everyone, but it’s especially important for people living with kidney disease, including those on dialysis or after a kidney transplant. Immunosuppressant medicines used after a transplant can increase the risk of skin cancer.
It’s also worth remembering that some medicines, including certain antibiotics, diuretics and antidepressants, can make your skin more sensitive to sunlight, meaning you may burn more easily.
- Wear SPF 30+ sunscreen every day, or SPF 50+ if you've had a transplant.
- Reapply sunscreen regularly when outdoors.
- Stay in the shade where possible, particularly between 12pm and 3pm.

Dialysis and Your Skin
Itching is common for people on dialysis and can occur before, during or after treatment. Dialysis can also contribute to dry or sensitive skin, making regular moisturising especially important.
Following the fluid advice given by your kidney team may also help, as dehydration can make dry skin worse.
Don't forget to take care of the skin around your dialysis access site. Keeping the area clean and following advice from your renal team can help reduce the risk of infection.
Skin After a Kidney Transplant
Many skin problems improve after a successful kidney transplant, but transplant recipients face some new challenges. The medicines used to prevent rejection (immunosuppressants) reduce the body's natural defences. This can make you more likely to develop skin infections, warts, acne-like rashes and, importantly, skin cancer.
For this reason, checking your skin regularly is important. Contact your healthcare team if you notice:
- A new mole or lump.
- Changes to an existing mole.
- A sore that doesn't heal.
- Any unusual or persistent skin change.
Looking after your skin may seem like a small part of managing PKD, but it can make a real difference to your comfort and wellbeing. Whether you're newly diagnosed, having dialysis or adjusting to life after a transplant, a few simple habits can help keep your skin healthy all year round.
Watch: Expert Advice on Skin Care and Kidney Disease
Watch our webinar with Consultant Nephrologist, Dr Jacqueline Nevols explaining why kidney patients are more vulnerable to skin problems, the link between immunosuppressants and skin cancer, and practical tips for staying sun safe throughout the year.
Watch on YouTube
If you'd like to discuss how we can support you or a loved one, learn more about our services or contact our team today.
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