PKD Charity-funded research at the University of Wolverhampton is exploring how a newly identified gene called ATMIN is involved in autosomal recessive polycystic kidney disease (ARPKD).

Results from the DRINK study show that it will be possible to run a large trial testing the effect of high water intake on ADPKD progression.

Final report from the investigators: Our hypothesis is that the proteins contained in the small vesicles (called exosomes) contained in the urine of ADPKD (Autosomal Dominant Polycystic Kidney Disease) patients reflect the disease stage and severity and can be used to identify biomarkers and evaluate risk of progression.